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Stephan A. Mueller

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Open access Sep 2026

Microglia Ablation and Downstream Effects in the Cerebrospinal Fluid Proteome.

Disease-related activation of glial cells leads to changes in the cerebrospinal fluid (CSF) proteome. However, assigning such protein changes to their cellular origins is often difficult. Here, we used microglia (and macrophage) depletion in mice to identify CSF proteins of microglial origin. Young mice were treated wi...

Sinja Buchner, Si-Hui Song, Stephan A. Mueller et al. · 0 citations
Open access Aug 2026

A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes

A reproducible human three-dimensional brain tissue model with neurons, astrocytes and microglia, replicating in-vivo-like maturation and enabling the study of Alzheimer’s disease-relevant perturbations and drug responses is developed.

Julien Klimmt, Carolina Cardoso Gonçalves, J. V. Montgomery et al. · 1 citation

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