Author

Stephanie Makdissi

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Open access Jul 2026

The minor spliceosome component U4atac regulates JAK/STAT signaling to modulate hematopoiesis and immune responses in Drosophila melanogaster.

It is revealed that mutations in U4atac affect the splicing of a large set of transcripts involved in innate immunity, hematopoiesis, and intestinal cell functions, including the Drosophila Janus kinase (JAK) homolog hopscotch (hop).

D. Shikara, Eden Bishop, Nathan Barton et al. · Nature Communications · 1 citation