Author

Stephen S. Rich

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Sep 2026

Integrated Risk Prediction of Kidney Failure: Clinical and Multi-Omic Approaches.

BACKGROUND Kidney failure affects approximately 800,000 adults in the United States, and African Americans carry a disproportionate burden of disease. Robust algorithms for clinical risk prediction, such as the Kidney Failure Risk Equation (KFRE), have previously been validated, whereas the clinical utility of polygeni...

Alana C. Jones, Atlas Khan, Amit Patki et al. · American Society of Nephrolo... · 0 citations

Open access Aug 2026

Genetic drivers of protein changes over time: Findings, considerations, and approaches in TOPMed cohorts and UK Biobank

Age is a major risk factor for many diseases, but the biological processes driving aging are heterogeneous across individuals. Efforts to untangle differences between chronological and biological age have focused on identifying age-associated markers, such as ’omics clocks. Many ’omics features, including proteins, are...

M. Gillman, H. Chen, A. Howard et al. · bioRxiv · 0 citations

Open access Jul 2026

Using Polygenic Risk Scores to Evaluate Definitions of Self-Reported Sleep Phenotypes Across Cohorts.

Which sleep PRS performed well across diverse populations and which sleep definitions better captured genetic underpinnings was highlighted by evaluating several types of sleep PRSs and sleep phenotypes.

A. Wyss, Michael Brown, Xiang Li et al. · Sleep · 0 citations