Steven S. Segal

Integrating and Orchestrating Multiple Components of Skeletal Muscle Injury and Regeneration.

As a soft tissue comprising nearly half of body mass, skeletal muscle is vulnerable to injury from many sources. Healthy muscle can regenerate from resident stem cells known as satellite cells (SCs). During homeostasis, individual SCs reside within a niche sandwiched between basal lamina (BL) and sarcolemma, dispersed...