Open access
Oct 2026
The bacterial iron sensor IdeR distinguishes DNA sequences by applying stress to non-cognate DNA
The transcription factor IdeR regulates iron homeostasis in many gram-positive bacteria. It primarily functions as a repressor of iron uptake genes by binding to their promoters and blocking RNA polymerase access. IdeR recognizes a highly conserved DNA sequence consisting of four palindromic 5’-C1C2T3A4A5 repeats. For...
Suvankar Ghosh, O. Koshla, D. Maurer et al.
· bioRxiv · 0 citations