Airway epithelial cell–lung macrophage crosstalk in type 2-high and low asthma endotypes: mechanisms and therapeutic strategies
Asthma is a heterogeneous chronic airway disease. Asthma endotypes are mainly classified as type 2-high and type 2-low, based on immunological and molecular mechanisms, providing a more comprehensive framework for understanding the underlying pathological processes. Airway epithelial cells (AECs) and lung macrophages c...