SET Oncoprotein in Gastric Cancer: A Master Regulator of PP2A Suppression and Tumor Progression
Gastric Cancer (GC) remains a major cause of cancer-related mortality worldwide, largely owing to late diagnosis, aggressive tumor behavior, and therapeutic resistance. The SET oncoprotein (I2PP2A), a potent endogenous inhibitor of Protein Phosphatase 2A (PP2A), has emerged as an important regulator of oncogenic si...