Open access
Sep 2026
Estrogen interactions with breast cancer risk variants in regulatory DNA
Ibtihal Elfaki, Laura N. Kellman, Robin M. Meyers et al.
· medRxiv · 0 citations
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Open access
Aug 2026
Lineage master regulator and cancer-selective partner transcription factors rewire 3D genome topology for tumor-specific gene control
It is shown that p63 reorganizes 3D chromatin topology in squamous cell carcinoma through cooperation with the tumor-selective partner TF, FOXK1, which defines an epigenetic mechanism by which a lineage master TF and tumor-restricted partner TF reshape 3D chromatin structure to drive oncogenic transcription, with impli...
N. Jung, V. Lopez-Pajares, L. Donohue et al.
· Science Advances · 0 citations