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Author

Suk Woo Nam

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Open access Aug 2026

CSTF2-mediated 3′UTR shortening drives oncogenic activation of GPC3 in hepatocellular carcinoma

Alternative polyadenylation (APA) generates mRNA isoforms with distinct 3′ untranslated regions (3′UTRs), thereby influencing transcript stability and translation. In cancer, 3′UTR shortening can activate oncogenes by escaping microRNA (miRNA)-mediated repression, but its role in hepatocellular carcinoma (HCC) remains...

Soyoung Jeon, Eunbi Shin, Woong-Ha Jin et al. · 0 citations

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