YY1 regulates B cell lineage plasticity via transcriptional, miRNA post-transcriptional, and epigenetic mechanisms 2299696
YY1 is essential for embryogenesis, cell proliferation, and lineage differentiation. It regulates genes via co-activators, co-repressors, or PcG complexes. In hematopoiesis, YY1 controls stem cell differentiation, and its loss at the pro-B stage halts B-cell development. Bulk RNA-seq of WT and YY1-KO pro-B...