From Antimicrobial Biomaterials to Infection-Resilient Interfaces: Engineering the Host, Microbe, and Material Interface Against Drug-Resistant Biofilms
Drug-resistant biofilm infections remain a major challenge for medical devices and implants. Biofilm formation can reduce antimicrobial effectiveness through physiological heterogeneity, tolerance, persistence, and interactions with the host and biomaterial surface. Antimicrobial biomaterials have been developed to pre...