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Open access Oct 2026

CNIH4 as a prognostic biomarker and promoter of malignant progression in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a molecularly heterogeneous malignancy with variable clinical outcomes. Although cornichon family AMPA receptor auxiliary protein 4 (CNIH4) has been implicated in several disease processes, its clinical and biological relevance in HNSCC remains incompletely defined....

Jun Chen, Aitao Nai, Ji-Jie Cai et al. · 0 citations
Aug 2026

E3 ubiquitin ligase SYVN1 promotes the malignant phenotype of A549 cells by upregulating GATA3 expression via NRP1.

Findings prove that SYVN1 could promote the malignant characteristics of A549 cells by modulating the GATA3/NRP1 axis and that targeting SYVN1 could represent a promising therapeutic approach for treating lung cancer.

Shan-Hu Wang, Suli Lu, Zhen Wang et al. · 0 citations

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