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Author

Suman Sinha

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3 papers indexed here

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Review Oct 2026

Emerging Therapeutic Protein Targets of Inflammation: A Comprehensive Review.

Conventional anti-inflammatory therapies, including nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids, remain the mainstay of treatment for inflammatory disorders. However, their long-term use is often limited by adverse effects, insufficient target specificity, and an inability to achieve sustained res...

Suman Sinha, Ram Kumar, Km Shainda · 0 citations
Sep 2026

Beyond the Hydrophobic Trough of Pf AMA1: Pivotal Roles of Cryptic Loop Dynamics Inform Anti-Malarial Therapeutic Design

Protein loops often mediate dynamic, conformation-dependent molecular recognition. This perspective examines the essential interaction between Plasmodium falciparum apical membrane antigen 1 (PfAMA1) and rhoptry neck protein 2 (PfRON2), which drives moving-junction formation and erythrocyte invasion. We focus on the...

Suman Sinha · 0 citations
Oct 2026

Beyond stacking: Recognition, egress, and dynamical relay of phen-DC3 at a quadruplex-duplex junction.

G-quadruplex-duplex (Q-D) junctions are structurally complex nucleic-acid architectures with emerging relevance as selective ligand-binding targets, yet the dynamic basis of ligand recognition and dissociation at these hybrid interfaces remains insufficiently characterized. Here we have conducted microsecond level equi...

Suman Sinha, Km Shainda · 0 citations

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