Development and validation of RP-HPLC for the Determination of Caspofungin in the Ufasomes Dispersion, Gel and Rat Plasma
Caspofungin is a lipopeptide echinocandin antifungal and its mechanism involves inhibition of (1,3)-β-D-glucan synthase, disrupting fungal cell wall integrity. This study presents a validated RP-HPLC method for detecting and quantifying CSP in ufasomes dispersion and rat plasma, providing a reliable and reproducible ap...