Sumbal Ijaz

Late-stage Functionalization Approaches for Dihydropyrimidinone Scaffolds: Recent Methods and Biological Relevance

3,4-Dihydropyrimidin-2(1H)-ones (DHPMs), synthesized via the classic Biginelli condensation, have emerged as pivotal heterocyclic frameworks with broad medicinal and synthetic relevance. Their intrinsic versatility enables downstream transformations that furnish a diverse spectrum of novel scaffolds. Although multi...