Review
Open access
Jul 2026
TUMOR MICROENVIRONMENT DYNAMICS: MOLECULAR AND GENETIC DETERMINANTS OF CANCER PROGRESSION AND THERAPY RESPONSE
The evidence demonstrates that growth factor signalling, inflammatory pathways, hypoxia, metabolic reprogramming, genetic and epigenetic alterations, and extracellular vesicle-mediated communication alter the tumour microenvironment, encouraging tumour growth, metastasis, immune escape, and resistance to immunotherapy, chemotherapy, radiation, and targeted treatment.
Dr. Gopalaxmi Nath, Moumita Ghosh, Dr Shahid Ahmad Shergojry et al.
· Genetics and Molecular Resea... · 0 citations