Sep 2026
Histone Deacetylase-Activatable BODIPY-Based G-Quadruplex Stabilizer Significantly Reducing Colon Cancer Proliferation
The first example of a histone deacetylase-activatable G4 ligand, displaying a significant stabilization upon activation (26 °C, ΔTm), was developed and has a promising therapeutic potential and can be a useful building block for the development of novel activatable G-quadruplex ligands.
Nezahat Gokce Ozsamur, Sundus Erbas-Cakmak
· Journal of Medicinal Chemist... · 0 citations