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Author

Sung-Gwon Lee

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3 papers indexed here

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Oct 2026

RNA-seq-based transcriptome analysis identifies TCR-expressing B1 cells as a multipotent lymphoid intermediate.

Classically, B and T lymphocytes are regarded as distinct lineages that can be readily distinguished by the receptors expressed on their surface. However, our recent study established that peritoneal B1 cells serve as precursors for extrathymic T cells through a TCR+CD19+ double-positive (DP) intermediate. To investiga...

Jeong-Eun Seon, Su-Min Yee, Sung-Gwon Lee et al. · 0 citations
Open access Aug 2026

Interpretable prediction of nucleic acid-binding proteins using a protein language model

It is demonstrated that attention-based protein language models can accurately identify nucleic acid-binding proteins directly from sequence data and reveal biologically meaningful sequence determinants of binding, establishing an interpretable and scalable framework for proteome-wide characterization of protein–nuclei...

Hanjin Kim, Sung-Gwon Lee, Joo-Seong Oh et al. · 0 citations
Open access Jul 2026

An openly licensed benchmark and per-gene calibration map for missense pathogenicity predictors on activating cancer drivers

An openly licensed framework is provided to interpret and recalibrate pathogenicity predictors such as AlphaMissense in the somatic setting rather than a replacement predictor, and a cancer-calibrated stack modestly improves discrimination over the best single tool.

Sung-Gwon Lee · 0 citations

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