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Sung-Woo Hong

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Open access Aug 2026

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

ABSTRACT Chiral alkyl selenides are valuable motifs in medicinal chemistry and redox‐active molecular design, yet enantioselective hydroselenylation of unactivated alkenes remains challenging due to limited control over regio‐ and enantioselectivity. Here, we report nickel‐hydride‐catalyzed enantio‐ and regioselective...

Hyung-Joon Kang, Jaehun Kim, Sung-Woo Hong · 0 citations
Open access Aug 2026

Structure-Based Virtual Screening and De Novo Design Guided by 3D-QSAR Triage for the Identification of Nanomolar STK3 Inhibitors

This study establishes a robust design paradigm for the rapid development of highly potent kinase inhibitors through structure-based computational strategies and indicates that 3D-QSAR modeling contributed as a complementary triage tool rather than a standalone driver of lead discovery.

Ahyoung Jang, Kewon Kim, Hyeonsoo Han et al. · 0 citations

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