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Open access
Sep 2026
Nanomedicine has progressed far beyond its early role as an experimental drug-carrier toolbox and today stands as a clinically validated enabling technology. Liposomal formulations and albumin-bound nanoparticles have transformed cancer therapy, while lipid nanoparticle (LNP) platforms accelerated the rapid development...
A. Grattoni, Marco M. Paci, Noah Arnold et al.
· Biomedical microdevices · 0 citations
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Review
Open access
Sep 2026
Unresolved DNA lesions trigger replication stress, forcing cancer cells to hijack DNA damage tolerance (DDT) networks, specifically translesion synthesis (TLS) and template switching, to sustain replication. While DDT prevents lethal fork collapse, error-prone TLS drives mutagenesis, tumor evolution, chemoresistance an...
Audesh Bhat, G. Lahane, R. Pandita et al.
· Trends in Cancer · 0 citations
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