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Author

Suriya Panneerselvam

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Aug 2026

Sinigrin Mitigates Pulmonary Inflammation and Fibrosis Partly through Adenosine Monophosphate-Activated Protein Kinase (AMPK) Signaling.

Gen and protein expression analyses demonstrated that SNG dose-dependently attenuated the bleomycin-induced inflammatory and fibrotic marker expression, and mechanistic investigations demonstrated that SNG exerts its anti-inflammatory and antifibrotic effects partly through activation of AMPK signaling.

Suriya Panneerselvam, J. S, Anoop Kishore et al. · 0 citations
Aug 2026

Pharmacological inhibition of CDK7 and CDK9 suppresses gastrointestinal (colon) cancer progression through modulation of stemness, epithelial-mesenchymal transition, and chemoresistance.

GNE-3511 exerts potent anticancer activity by disrupting CDK7/9-dependent transcriptional programs that regulate proliferation, apoptosis, stemness, EMT, and multidrug resistance and is identified as a potential lead candidate for the treatment of colorectal cancers.

Nidhi Sharma, Suriya Panneerselvam, Sandip B. Bharate et al. · 0 citations

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