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Susana M. D. A. Garcia

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Review Open access Oct 2026

Disruption of RNA metabolism and its impact on protein homeostasis

Abstract Repeat-associated disorders arise from expansions of nucleotide repeats in coding or non-coding regions, producing RNAs that accumulate and disrupt cellular homeostasis through mechanisms collectively termed RNA repeat toxicity. This process complements proteotoxicity in coding-region expansions and is increas...

Susana M. D. A. Garcia · 0 citations

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