Review
Open access
Sep 2026
The BRCA1-A complex: At the edge of resection and the beauty of restraint.
How a DNA double-strand break (DSB) is repaired by the cell is organized around a fundamental decision between DNA end protection and 5'-end resection. BRCA1 is a central regulator of this choice, promoting DNA end resection in the S and G2 phases of the cell cycle to stimulate error free repair by homologous recombina...
Светлана Вячеславовна Антонова, V. Mangkusaputra, A. Schreuder et al.
· DNA Repair · 0 citations