Jul 2026
Abstract A083: Integrated multi-omic analysis and CRISPR screening identify GPX2 as a critical vulnerability in high-risk lung adenocarcinoma
An integrated multi-omic approach presented here identified GPX2 as a critical vulnerability in a well-defined LUAD subpopulation and provides a rationale for targeting the NFE2L2/GPX2 axis, offering a strategic opportunity for therapeutic intervention.
A. Singhania, K. Bastian, Y. Shah et al.
· Clinical Cancer Research · 0 citations