Development and Validation of a Reversed-Phase Stability-Indicating HPLC Assay Method for the Simultaneous Determination of Esomeprazole Magnesium Trihydrate and Itopride Hydrochloride in Solid Dosage Forms
An isocratic reversed-phase high-performance liquid chromatographic method was developed for the simultaneous determination of esomeprazole magnesium trihydrate and itopride hydrochloride in bulk drug and solid dosage forms. Separation was achieved on a HiQ Sil C18HS column (250 mm×4.6 mm, 5 μm) using a mobile phase co...