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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Syeda Farwa Naqvi

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Oct 2026

Computationally Guided Design and Biological Evaluation of New Benzoxazole Bridged thiazole based 1,3-Oxazole Conjugates as Potential Anti-Alzheimer's Agents: Molecular Docking, DFT and sADMET Studies

Alzheimer's disease (AD) remains one of the most devastating neurodegenerative disorders, characterized by progressive cognitive impairment associated with cholinergic dysfunction. In pursuit of potent dual cholinesterase inhibitors, a series of structurally diverse benzoxazole linked thiazole based 1,3-oxazole molec...

Syeda Farwa Naqvi, Hina Sarfraz, Abdul Rehman et al. · 0 citations
Aug 2026

Identification, Design and Computational Insights of Hybrid Thiadiazole Linked Fused Thiazole-Isoxazole as Potent Dual Inhibitor of AChE/BChE Alzheimer's Disease

Alzheimer’s disease (AD), involves progressive cognitive impairment primarily associated with cholinergic dysfunction. Dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) continue to represent a validated and clinically relevant therapeutic approach for alleviating cholinergic deficits in...

Y. Khan, Hina Sarfraz, Azmatullah Khan et al. · 0 citations
Review Aug 2026

Multitargeted drug strategies for Alzheimer’s and Parkinson’s diseases

Recent advances in multitarget drug development for AD and PD targeting compounds targeting Aβ, BACE1, MAO-B, cholinesterases, metal-ion dyshomeostasis, oxidative stress, and inflammatory pathways are reviewed.

Azmatullah Khan, Abdullah Abdullah, Syeda Farwa Naqvi et al. · 0 citations

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