Engineered microbial immunotherapies can localize immune-modulating signals within solid tumors, where hypoxia, suppressive myeloid cells, deficient antigen presentation, and dysfunctional T-cell trafficking often limit immunotherapy. Macrofungal polysaccharides, especially structurally defined β-glucans, offer mecha...
K. E. Dunga, Sylvester Chibueze Izah, E. R. Aseibai et al.· Frontiers in Oncology· 0 citations
Flooding is commonly approached as a hydrological disaster, followed by emergency relief, disease surveillance, and environmental clean-up. This approach appears incomplete because floodwater rapidly connects contaminated land, failed sanitation systems, agricultural areas, industrial facilities, water-supply infrastru...
Sylvester Chibueze Izah, M. Ogwu, V. I. Promise et al.· Frontiers in Water· 0 citations
Soil-contaminant risk is commonly screened using total concentrations, yet the total fraction alone does not establish biological exposure, ecological impairment, or recovery of soil functions. This Perspective proposes a function-centered extension of established risk assessment, linking sources and legacy stores to s...
Sylvester Chibueze Izah, E. R. Aseibai, V. I. Promise et al.· Frontiers in Soil Science· 0 citations
Male reproductive health reflects coordinated spermatogenesis, endocrine regulation, reproductive-tract patency, sexual function, and sperm genomic integrity. This scoping review maps evidence on environmental exposures, pharmacological agents and substance use, and acute or chronic diseases that may influence these do...
Sylvester Chibueze Izah, K. E. Dunga, E. R. Aseibai et al.· Frontiers in Endocrinology· 0 citations
This narrative review evaluates how convincingly plant-food components and plant-rich dietary patterns influence neuroinflammation and whether those mechanisms translate into neurological benefit. Infection is treated as one possible initiating exposure, neuroinflammation as a context-dependent mechanism, and neurologi...
K. E. Dunga, Sylvester Chibueze Izah, A. Dunkwu-Okafor et al.· Frontiers in Nutrition· 0 citations
Mushroom-derived polysaccharides are widely promoted as anticancer immune modulators, but interpretation is weakened by imprecise product identity, chemically non-equivalent preparations, and extrapolation across evidence levels. This critical narrative review evaluates beta-glucans, heteropolysaccharides, polysaccha...
Sylvester Chibueze Izah, E. R. Aseibai, K. E. Dunga et al.· Frontiers in Oncology· 0 citations
Healthcare students demonstrated good knowledge and awareness/attitude of AMR; however, inappropriate practices persisted and the gap between knowledge and behaviour highlights the need for practical, behaviour-focused stewardship training and improved analytical approaches in future studies.
Sylvester Chibueze Izah, Princewill C. Igbojinwaekwu, Moses Amaefula et al.· Discover Public Health· 0 citations
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