BackgroundThere is an ongoing quest for novel biomarkers which may serve as therapeutic targets in cognitive impairment, alongside a growing appreciation of urinary metabolomics as a promising non-invasive approach to identify metabolic signature of Alzheimer's disease and other causes of dementia.ObjectiveWe studied w...
Serena Low, Hui-Li Zheng, A. Moh et al.· Journal of Alzheimer's Disea...· 0 citations
Pathway‐specific polygenic risk scores (psPRS) provide insights into the heterogeneity of type 2 diabetes. We aim to study whether psPRS for beta cell dysfunction, obesity and metabolic syndrome associate with risk of hyperglycaemic progression in Southeast Asian patients with type 2 diabetes.
Sylvia Liu, Hui-Li Zheng, Jia Le Ivan Tan et al.· Diabetes, obesity and metabo...· 0 citations
Novel proteins involved in axon guidance, immune response, inflammation, and metabolism associated with LOGC in youth-onset T2D with proteins demonstrating consistent associations across the lifespan and proteomic platforms are identified.
K. Tommerdahl, Kristen R. Miller, Jian-Jun Liu et al.· Journal of Clinical Endocrin...· 0 citations