T. A. Bogale

A selective JNK3-targeting miniprotein confers neuroprotection in a mouse model of ischemic stroke

Ischemic stroke remains a leading cause of death and long-term disability, and current reperfusion therapies do not prevent progressive neuronal loss and neurological decline. Thus, therapeutic strategies targeting intracellular pathways underlying post-ischemic neurodegeneration remain a critical unmet clinical need...