T. Addissouky

Integrating immunometabolic reprogramming and regulated cell death pathways in sepsis-induced myocardial dysfunction

Sepsis-induced myocardial dysfunction contributes substantially to mortality in critically ill patients, yet mechanistically targeted therapies remain limited. Macrophage immunometabolic reprogramming has been proposed as a candidate link between systemic inflammatory cascades and cardiomyocyte energetic collapse, but...