Hepatocellular carcinoma (HCC) develops within a chronically inflamed and immunologically dysregulated hepatic microenvironment that contributes to therapeutic resistance and disease progression. Gasdermin-mediated pyroptosis has emerged as a context-dependent inflammatory cell-death program capable of reshaping antitu...
T. Alramadneh, Inoyatillo Kholmurodov, Naina Boboyeva et al.· Clinical Immunology· 0 citations
Extracellular vesicle (EV)-associated non-coding RNAs (ncRNAs) are increasingly recognized as mediators of intercellular communication within the tumor microenvironment (TME), yet their mechanistic and translational significance varies substantially across gastrointestinal and hepatobiliary cancers. This narrative revi...
T. Alramadneh, Waleed K. Abdulsahib, Sanan Thaer Abdal-Wahab et al.· Cancer Treatment and Researc...· 0 citations
Minimal residual disease (MRD) denotes the persistence of malignant cells below the detection limits of conventional diagnostics and is a principal determinant of relapse and therapeutic failure. Enhancing MRD detection is therefore essential for precision oncology. Tumor‑derived circular RNAs (circRNAs)-covalently clo...
T. N. Alramadneh, Hussein salim abed, Sarah Qutayba Badraldin Qutayba Badraldin et al.· Journal of Investigative Med...· 0 citations
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