Author

T. Apalata

2 papers indexed here

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Open access Aug 2026

Mixed-strain infection and heteroresistance in drug-resistant tuberculosis: insights from a whole-genome sequencing pilot

Background Mixed-strain Mycobacterium tuberculosis (M. tuberculosis; Mtb) infections and heteroresistance are increasingly recognized as under-detected contributors to drug resistance dynamics. In high-burden rural settings such as the Eastern Cape, these genomic features may reflect both within-host diversity and ongo...

Mandlenkosi Manika, L. Faye, N. Dlatu et al. · Frontiers in Epidemiology · 0 citations

Open access Sep 2026

Network Analysis of Ct-Derived Molecular Resistance Marker Pathways in Mycobacterium tuberculosis: Deciphering Drug-Resistance Architectures in Rural Eastern Cape, South Africa

Background Drug-resistant tuberculosis remains a major public health challenge, particularly in high-burden settings where rapid characterization of resistance patterns is important for surveillance. Molecular diagnostics routinely detect resistance-associated targets, but these are commonly evaluated individually. T...

Kamvelihle Sabisa, N. Sineke, K. Mpofu et al. · F1000Research · 0 citations