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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

T. Avşar

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Open access Sep 2026

Selinexor enhances temozolomide efficacy in glioblastoma through modulation of multiple resistance-associated mechanisms

Introduction Glioblastoma remains one of the most treatment-resistant cancers, and temozolomide (TMZ) resistance is a central barrier to durable clinical response. Inhibition of exportin-1 (XPO1) by selinexor has emerged as a promising strategy to overcome resistance in solid tumors; however, its ability to sensitize T...

Beyza Ozturk, A. Çelebi, D. Kılıç et al. · 0 citations
Open access Aug 2026

Targeting BCL‑2 through Deep Learning-Based Drug Repurposing: A Multimodal Approach Combining Diffusion-Based Generative Modeling, Neural Relational Inference, and In Vitro Validation

A multimodal BCL-2 repurposing workflow built with diffusion-based generative modeling for ligand-specific complex generation and an extended neural relational inference (NRI) framework for trajectory-level interaction analysis is presented, establishing a strategy that couples generative complex prediction with graph-...

Ehsan Sayyah, H. Tunc, A. Çelebi et al. · 0 citations

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