Author

T. Azad

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Open access Oct 2026

A ribosomal pseudouridine drives an oncogenic translation program

Ribosome heterogeneity can regulate translation, but how changes in ribosome chemistry reshape cellular programs and contribute to diseases such as cancer remains incompletely understood. Here we show that SNORA81-guided pseudouridylation at a single 28S ribosomal RNA site, U4636, links ribosome heterogeneity to select...

Laurence Faucher-Giguère, Andrea Rivera-Pizana, Baudouin Seguineau de Préval et al. · bioRxiv · 0 citations

Open access Oct 2026

A ribosomal pseudouridine drives an oncogenic translation program

Dynamic ribosome heterogeneity has emerged as a potential layer of translational regulation, but whether variation in ribosomal RNA (rRNA) modification stoichiometry can selectively control the translation of mRNAs with shared encoded features remains unclear. Here we show that SNORA81-guided pseudouridylation at U4636...

Laurence Faucher-Giguère, Andrea Rivera-Pizana, Baudouin Seguineau de Préval et al. · bioRxiv · 0 citations

Open access Sep 2026

A Proposal for an Ultrasensitive Label-Free Optical BioMEMS Platform Based on a DBR-Michelson Interferometer for Cancer Detection and Therapeutic Applications

Early detection of cancer remains challenging due to the extremely low concentration of biomarkers present during initial disease stages. Dysregulation of key signaling pathways, including cyclin-dependent kinase (CDK) networks, drives uncontrolled cell proliferation and tumor progression, underscoring the need for hig...

Bocar Ndiaye, N. Brahiti, K. Nouri et al. · Italian National Conference... · 0 citations