The translation of abstract cognitive intention into localised physical action is a defining feature of voluntary behaviour1,2. To achieve this, the brain must maintain a highly regulated preparatory state, yet the macroscopic architecture of this interface remains elusive. Historically, the primary motor cortex has be...
Chen Zheng, Shi-Tong Xiang, Chao Xie et al.· Research Square· 0 citations
Aggression in mental disorders (AMD) is a prevalent symptom, poses difficulties to the clinical setting and has far-reaching societal implications. The biological basis of different manifestations, developmental courses, and disease-specific mechanisms remains largely unknown. The lack of understanding of the complex m...
U. Habel, A. Reif, S. Herpertz et al.· BMC Psychiatry· 0 citations
Objective Reliable and valid diagnostic interviews for preschool-age children are needed to identify children with externalizing behavior problems requiring treatment and thus prevent adverse outcomes. This study evaluated the psychometric properties of the semi-structured Clinical Parent Interview for Externalizing Di...
Lea Teresa Kohl, F. Oswald, Ann-Kathrin Thöne et al.· PLoS ONE· 0 citations
Changes in personality during adolescence may shape future alcohol use, especially in times of societal crisis. The COVID-19 pandemic disrupted social norms and stress regulation, making it a natural experiment to examine how early-life personality trajectories predict later substance use. Using longitudinal data from...
Rabia Zohair, K. Janson, Sebastian Siehl et al.· Scientific Reports· 0 citations
Adolescence represents a developmental phase marked by profound and rapidly shifting emotional states. While some adolescents exhibit pronounced, day-to-day mood variability, others remain comparatively stable. Although emotional fluctuation has long been considered a core feature with implications for health and well-...
C. Borzikowsky, M. Prignitz, Stella Guldner et al.· Scientific Reports· 0 citations
Early detection and prevention of psychiatric disorders, particularly depression, remain as major global health challenges, yet reliable tools for identifying individuals before symptom onset are lacking. Here, we combine functional neuroimaging with computational modeling to identify a mechanistic biomarker of depress...
Han Lu, Xiaoqian Yan, Benjamin Becker et al.· Science Advances· 0 citations
It is demonstrated that different environments generate distinct biological associations with brain maturation, which underscores the need to consider both grey and white matter when assessing the neurodevelopmental pathways to outcomes across the lifespan.
Lea C. Michel, D. Rakesh, T. Banaschewski et al.· bioRxiv· 0 citations
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