The neural mechanisms supporting delayed threat memory recall in humans remain poorly understood. Animal studies indicate that the paraventricular nucleus of the thalamus (PVT) contributes to threat-memory retrieval after longer retention intervals, but whether the human PVT shows cue-related discriminability during de...
Cassandra Hayashi, Coty Chen, M. Yassa et al.· Neurobiology of Learning and...· 0 citations
It is found CRH signaling via CRHR1 indeed disrupts reward behaviors in naïve mice, but is dysregulated in ‘anhedonic’ mice with a history of ELA, and activation of CRH receptor 2 (CRHR2) reverses anhedonia-like behaviors in adult ELA mice.
Matthew T. Birnie, Lara Taniguchi, Lia M. Harvey et al.· bioRxiv· 0 citations
Predictability, the degree to which environmental inputs are structured, patterned, and reliably signaled over time, has emerged as a central dimension of early experience with unique implications for brain development, stress physiology, and mental health. This review synthesizes convergent evidence from human and ani...
Mason Hardy, T. Baram· Annual Review of Development...· 0 citations
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