Hypertension is the leading modifiable risk factor for cardiovascular disease globally, driven by a sodium-rich, potassium-poor dietary phenotype. Whilst potassium-enriched salt substitutes (PESS) demonstrate hypotensive potential, widespread clinical implementation is hindered by theoretical concerns regarding f...
G. Â. Alves, T. Bonafé, B. Souza et al.· European Heart Journal· 0 citations
Although the intervention does not significantly reduce motor symptoms, it may be associated with consistent benefits in anxiety and constipation-related quality of life, suggesting an overall improvement in quality of life.
Matheus de Souza Ribeiro, T. Bonafé, Heloísa Rodrigues Bariviera et al.· ANPAbstract_CBN26· 0 citations
Hypertension remains the leading modifiable risk factor for cardiovascular disease, yet control rates are suboptimal due to poor adherence and blood pressure (BP) variability with daily oral regimens. Zilebesiran is an investigational RNA interference therapeutic targeting hepatic angiotensinogen (AGT) synthesis....
T. Bonafé, G. A. Alves, B. M. Gomes et al.· European Heart Journal· 0 citations
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