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T. Budhy

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Review Open access Jul 2026

The Role of PD-1 and CTLA-4 Blockade in Immunotherapy: Mechanisms of Action and Therapeutic Efficacy in Overcoming Lung Cancer Immune Evasion

It is found that ICI monotherapy significantly improves overall survival in NSCLC with PD-L1 expression ≥50% compared with platinum-based chemotherapy, and first-line atezolizumab plus chemotherapy extended median overall survival to 12.3 months, compared with 10.3 months in extensive-stage SCLC.

Mojeeb Abdo Abdullah Qasem, T. Budhy, D. Suprabawati et al. · 0 citations