The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae undermines treatment efficacy, while limited genomic epidemiological data constrain understanding of local transmission dynamics. We therefore aimed to investigate the genomic epidemiology and the antimicrobial resistance landscape of K. pneumoniae in ter...
Aiman Waheed, S. Khan, Taj Ali Khan et al.· AIMS Microbiology· 0 citations
Host genetic variation is a key determinant of malaria susceptibility, particularly in endemic regions where intense transmission has driven strong selective pressures on red blood cell-related genes. However, Senegalese and other African populations remain underrepresented in genomic studies, limiting population-speci...
Babacar Souleymane Sambe, A. Diagne, J. Phelan et al.· International Journal of Mol...· 0 citations
Background: The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Salmonella enterica serovar Typhi has severely constrained typhoid treatment. Pakistan is a major hotspot for XDR typhoid, yet genomic evidence defining the molecular basis of antimicrobial resistance, virulence, and genomic div...
Rabia Mehr, Qaisar Ali, M. Zahid et al.· Microorganisms· 0 citations
TB-Profiler is a user-friendly bioinformatics tool developed to genotypically profile
Mycobacterium tuberculosis
from next-generation sequencing data. It provides predictions of drug resistance and assigns sub-lineages to support clinical management of tuberculosis (TB) and public health surveillance. The pla...
J. Phelan, Waritta Sawaengdee, Joseph Thorpe et al.· Genome Medicine· 0 citations
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