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The findings suggest that S4 treatment is associated with significant alterations in breast cancer growth and metabolic pathways, and suggests that S4 exploits unique metabolic vulnerabilities, supporting further investigation of SARMs in breast cancer models.
By integrating molecular vaccine design with tumor evolution, immune-contexture remodeling, and checkpoint sensitivity, this review identifies determinants that may distinguish successful immune priming from durable therapeutic efficacy and outlines priorities for biomarker-guided patient selection and future combinati...
This review synthesizes the biological rationale, technical principles, and translational applications of PDO–OoC integration, with an emphasis on recent clinical validation studies, AI integration, and post-FDA Modernization Act 2.0 regulatory evolution.
Initial evidence is provided that marbofloxacin induces metabolic and molecular rewiring in BC, highlighting its promise as a repositionable therapeutic candidate.
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