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Open access Aug 2026

Context-dependent regulatory networks connect Alzheimer’s disease genetics to microglial inflammatory responses

Inflammation is central to Alzheimer’s disease (AD) pathogenesis. Microglia, the resident innate immune cells of the brain, exhibit diverse inflammatory states and are enriched for AD-associated genetic variants within active cis-regulatory elements (CREs). However, the interplay among genetic variants, transcription f...

Ting-Ting Fu, Margareta Kurkela, Jia-Yong Tu et al. · 0 citations

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