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T. Fujisawa

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Review Open access Sep 2026

Landscape of cancer genomics and precision oncology in Japan, South Korea, China, and Australia

Summary Precision oncology has expanded rapidly across the Asia–Pacific region, yet implementation remains heterogeneous because of differences in health-system organisation, reimbursement, molecular tumour board infrastructure, workforce capacity, and data integration. This structured narrative review with expert cons...

H. Bando, H. Okayama, Yoon Jung Chang et al. · 1 citation
Open access Sep 2026

Age-related tumor mutational burden and inflammaging: a pan-cancer multi-omics study of treatment-naïve patients

Background Aging is a major nonmodifiable risk factor for cancer, yet age-associated genomic instability, inflammatory activation, and tumor microenvironment interactions remain poorly characterized. Patients and methods The primary genomic cohort comprised 153 treatment-naïve patients with six cancer types, stratified...

S. Yajima, Y. Tsukada, Y. Sota et al. · 0 citations
Review Open access Jul 2026

AI-integrated multi-omics platform to revolutionize anti-metastatic therapy development through circulating tumor cell profiling: SCRUM-MONSTAR-CTC

It is proposed that the next phase of precision oncology should integrate the cellular dimension of metastasis through systematic circulating tumor cell (CTC) profiling and highlights adherent-to-suspension transition (AST) as one representative, experimentally tractable plasticity program that enables tumor cells to s...

T. Hashimoto, T. Shibuki, T. Fujisawa et al. · 0 citations

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