T. Gholipourshahraki

Estimating Within- and Between-Family Polygenic Effects For Psychiatric Disorders Under Non-random Ascertainment

Background: Polygenic scores (PGSs) are increasingly used to investigate the genetic architecture of complex traits. In genetics, family study designs are often used to adjust for confounders such as population structure and shared environment. However, family studies may also be particularly vulnerable to to non-rando...