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T. Giessen

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Jul 2026

Bacterial Geosmin Biosynthesis is Compartmentalized Inside a Two-Component Protein Shell

It is shown that GeoA cargo loading is mediated by repeating, short cargo loading peptides (CLPs), and that GeoA encapsulation provides benefits for enzyme activity and stability, and provides insights into a putative mode of cargo protein regulation via pore state modulation.

A. Fazal, Cassandra A. Dutcher, Michael P. Andreas et al. · 0 citations