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T. Giorgino

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Open access Oct 2026

Structural dynamics and pH‐regulated membrane binding of the TRAF2‐NC trimer

Abstract Tumor necrosis factor receptor‐associated factor 2 (TRAF2) is a key adaptor in TNF receptor‐signaling that operates as a trimeric assembly. Here we investigate the structural and functional properties of a TRAF2 construct spanning the trimerization and receptor‐binding domains (TRAF2‐NC, residues 266–501). Acc...

F. Cossu, Serena Virili, Bianca Braggiotti et al. · 0 citations
#generative ai Open access Oct 2026

AI and the PI: Infinite Generation, Finite Understanding

Generative artificial intelligence (AI) produces code and prose quickly, apparently enabling a principal investigator (PI) in a computational group to do more. Assessing this gain must also account for the laboratory’s role in training scientists who understand, maintain, and own their work. AI creates a generation–v...

T. Giorgino · 0 citations

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