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T. Halazonetis

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Open access Sep 2026

Human POLD3 coordinates leading and lagging strand mitotic DNA synthesis

Cancer cells are characterized by the presence of oncogene-induced DNA replication stress. A common consequence of replication stress is failure to complete DNA replication in S-phase, in which case, DNA replication may be completed in mitosis by a variant of Break-Induced Replication (BIR) called Mitotic DNA Synthes...

Demetrio Turati, Vasilios S. Dionellis, L. Tropia et al. · 0 citations

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