Author

T. Hansen

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Open access Aug 2026

Genetic architecture of cytokine autoantibodies and associated risk of common diseases

Anti-cytokine autoantibodies are increasingly recognized as modulators of immune function and determinants of disease risk, yet their genetic basis and population-level impact remain unclear. Here we perform genome-wide association studies of autoantibodies against IL-1α, IL-6, IL-10, IFN-α, IFN-β, IFN-γ and GM-CSF in...

J. V. von Stemann, Joseph Dowsett, R. Teglgaard et al. · Nature Communications · 0 citations

Open access Sep 2026

Evaluating the consequences of childhood adiposity on the human plasma proteome at four timepoints across the lifecourse

Applying a lifecourse approach using human genetic data, we evaluate the effect of childhood adiposity on the circulating proteome using measurements taken at four key life stages. Using lifecourse Mendelian randomization, we find genetically predicted childhood adiposity to have an effect on 8 proteins measured duri...

Phoebe Dickson, G. Power, L. Niu et al. · Nature Communications · 0 citations