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T. Hartung

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Open access 2026

A roadmap for modernizing vaccine safety assessment: Challenges and opportunities for new approach methodologies.

Vaccines are administered to large populations of healthy individuals, including vulnerable groups, making an exceptionally rigorous safety profile a prerequisite for their approval and use. Nonclinical vaccine safety assessment has traditionally relied on standardized animal testing methodologies, which face increasin...

F. Sillé, Paul Désert, Robert H. Levis et al. · 0 citations
Open access Aug 2026

The data substrate of exposome intelligence: an interoperability profile for untargeted metabolomics

Untargeted metabolomics, anchored in high-resolution mass spectrometry, has matured into the central analytical platform of human exposomics. It can capture endogenous biology, diet, drugs, microbial chemistry, environmental contaminants, and their transformation products from a single biological sample. Yet exposome s...

T. Hartung · 1 citation

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