Summary Understanding host-pathogen interactions during Mycobacterium tuberculosis (Mtb) infection has largely relied on identifying bacterial genes essential for intracellular survival. However, conventional reverse genetics approaches often overlook host pathways that regulate Mtb growth. Here, we developed a backtra...
Jayendrajyoti Kundu, Vishawjeet Barik, Abhijit Paul et al.· iScience· 0 citations
Pulmonary fibrosis and acute respiratory distress syndrome (ARDS) are the clinical challenges among patients with post-acute sequelae of COVID-19 (PASC), affecting ~ 10% of the survivors worldwide. PASC manifestations include pulmonary fibrosis, impaired respiratory function, and long-term morbidity. Recent WHO reports...
Garima Joshi, Gulistan Parveen, Simrandeep Kaur et al.· Journal of Translational Med...· 0 citations
ABSTRACT Coxiella burnetii is an obligate intracellular bacterial pathogen that causes the zoonotic disease Q fever. Coxiella extensively subverts host vesicle traffic and replicates within lysosome-derived, spacious vacuoles by secreting a suite of effectors through the type IVB secretion system (T4BSS). This study in...
Hrithik Kumar, Amrita Bhattacharya, Sayanthana Benny et al.· Infection and Immunity· 0 citations
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