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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

T. Kaisho

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Open access Sep 2026

Hypomorphic Lig4 gene mutation in mice predisposes to Th1-skewed intestinal inflammation.

DNA ligase IV (LIG4) is essential for DNA double-strand break (DSB) repair. Hypomorphic LIG4 variants cause LIG4 syndrome, characterized by growth disturbance, increased radiosensitivity, predisposition to malignancies, adaptive immunodeficiency and inflammatory conditions. Most of these manifestations are recapitulate...

Yusuke Yamashita, Hideki Kosako, Takashi Kato et al. · 0 citations
Open access Aug 2026

46 Anti-tumour immune responses in melanoma brain metastases require cDC1 population and the extracranial tumour

It is hypothesize that extracranial tumour inhibits intracranial tumour growth through extracranial cDC1-mediated priming and expansion of CD8+ T cells which then home to intracranial tumours, by directly enhancing the activation of intracranial cDC1s, or a combination of both.

Dario Guglietta, Alca Revalova, Fiona R. James et al. · 0 citations

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